A new approach to understanding hereditary and multifactorial/common diseases, based on the integration of the results of a comprehensive study of their pathogenomics with the use of mathematical and bioinformatical analyzes, made it possible to revise the initial provisions of predictive medicine in accordance with the rules of modern "exact medicine". The publication consists of two parts. The first part presents the history of predictive medicine, its evolution, progress in the study of the...